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Science 351 , 12081213 (2016)

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The Smith patent references the treatment of disease by restoration of antioxidant function, but does not reference improvement by restoring the function of the remethylation of methionine, not does it reference the use of reduced glutathione as a single entity in a liposome

Subsequent studies showed that several GlyT1 inhibitors were effective in preclinical models predictive of antipsychotic and procognitive effects, including models relevant to Alzheimers disease and cerebral ischemia